{"id":139137,"date":"2024-07-25T10:56:17","date_gmt":"2024-07-25T10:56:17","guid":{"rendered":"https:\/\/websitedesigns.com.au\/elankanew\/?p=139137"},"modified":"2024-07-25T10:58:35","modified_gmt":"2024-07-25T10:58:35","slug":"decoding-liver-enzymes-what-you-need-to-know-by-dr-harold-gunatillake","status":"publish","type":"post","link":"https:\/\/websitedesigns.com.au\/elankanew\/decoding-liver-enzymes-what-you-need-to-know-by-dr-harold-gunatillake\/","title":{"rendered":"Decoding Liver Enzymes: What You Need to Know &#8211; By Dr Harold Gunatillake"},"content":{"rendered":"<h2 style=\"text-align: center;\"><span style=\"color: #800080;\"><strong>Decoding Liver Enzymes: What You Need to Know &#8211; By Dr Harold Gunatillake<\/strong><\/span><\/h2>\n<p><img loading=\"lazy\" loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-77916 aligncenter\" src=\"https:\/\/websitedesigns.com.au\/elankanew\/wp-content\/uploads\/2021\/11\/Harold-Gunethilake.jpg\" alt=\"Harold-Gunethilake\" width=\"160\" height=\"160\" \/><\/p>\n<p style=\"text-align: center;\"><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/_L5gzaev97o?si=dY3KnCc_V6Rb2wek\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<p><span style=\"font-size: 16px; color: #000000;\">Web :\u00a0<a style=\"color: #000000;\" href=\"https:\/\/doctorharold.com\/\" target=\"_blank\" rel=\"noopener\">doctorharold.com<\/a><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">Symptoms of liver disease may not be present until the later stages of severe disease, elevated liver enzyme tests are sometimes the first indication of potential liver damage. Hello viewers, today we will discuss liver enzymes and their significance. Liver enzymes are essential for our overall health, and understanding their importance can help clarify confusing lab results. Let&#8217;s delve into this.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">Welcome back to our channel. Today, as I said, we\u2019re delving into a topic that might have left you scratching your head during your last doctor\u2019s visit: liver enzymes. Don\u2019t worry; we\u2019ve got you covered! I\u2019m Dr. [Harold], and this is our mini crash course on liver enzymes and their significance.\u201d<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\"><strong>1. What Are Liver Enzymes?<\/strong><\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">&#8220;Okay, let\u2019s start with the basics. Liver enzymes are like the backstage crew of your body\u2014they work tirelessly behind the scenes to keep things running smoothly. Liver enzymes are proteins found in the liver that speed up specific chemical reactions within the organ.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">The two most common liver enzymes are:<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">Aspartate aminotransferase (AST)<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">Alanine aminotransferase (ALT)<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">These enzymes perform vital functions in the liver, but if the liver is damaged, AST and ALT can pass into the bloodstream. This causes their levels in the blood to rise, which can indicate an issue with liver health. Hope you got that right.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">Now, let\u2019s discuss elevated Liver Enzymes and Liver Health Elevated liver enzyme levels can be a sign of severe liver disease. Still, they can also occur with mild, temporary illnesses. Symptoms of liver disease may not be present until the later stages of severe disease, so elevated liver enzyme tests are sometimes the first indication of potential liver damage.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">Further testing is often required to determine the cause of elevated liver enzymes.AST and ALT hold great clinical significance as their increase (or rapid decrease) in blood serum can indicate problems within the liver, as mentioned That is what we check on a blood test to determine the liver&#8217;s functional situation.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">Here\u2019s what the enzymes do: Metabolising Nutrients and Medications within the liver cells: Liver enzymes help break down your food and medications.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">Think of them as the ultimate multitaskers.<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">1. The liver is an essential metabolic organ rich in enzyme systems that play an important role in the metabolism and protein synthesis in the body.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">Specifically, it is applied to degrade toxins, secrete bile, store glycogen, and metabolise drugs What food does the liver break down? It breaks down fats eaten, converting excess carbohydrates and protein into<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">forms stored for later use while synthesising other fats, like cholesterol.\u00a0<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">2. Bile is a fluid made and released by the liver and stored in the gallbladder. It helps with digestion by breaking down fats into fatty acids, which the digestive tract then takes into the body.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">Bile is a superhero substance that helps digest fats and absorb fat-soluble vitamins in the gut. Without bile, your intestines would throw a little tantrum.&#8221; As mentioned, You need your liver to digest anything you eat with fat. Every day, your liver cells make almost a litre of bile, a dark green liquid that flows into tubes called bile ducts. From there, the bile passes into the duodenum, a section of your small intestine, where it breaks the fat into smaller particles.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\"><strong>The Three Main Liver Enzymes<\/strong><\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">&#8220;Okay, let\u2019s meet the stars of our show\u2014the three main liver enzymes:<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\"><strong>1. Aspartate Aminotransferase (AST)<\/strong>: This one\u2019s like the drama queen. AST is a marker for liver cell injury. But guess what? It\u2019s not exclusive to the liver. It also pops up when your muscles are unhappy (like after a vigorous workout) or during a heart attack, or it may be a sign of heart problems and pancreatitis, or it may be a sign of hepatitis.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\"><strong>Alanine Transaminase (ALT)<\/strong>: ALT is the true liver specialist. When it\u2019s elevated, it\u2019s like the liver waving a tiny red flag, saying, \u2018Hey, something\u2019s up!\u2019 ALT is specific to the liver, so it\u2019s our most valuable player<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\"><strong>2. Alkaline Phosphatase (ALP)<\/strong>: ALP is the detective. It\u2019s linked to bile duct injury. Those bile ducts are like the liver\u2019s secret tunnels\u2014they carry bile to your intestines. ALP also moonlights in bone and even during pregnancy.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">High alkaline phosphatase levels in your liver may be a sign of bile duct blockages, cirrhosis, or hepatitis.<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">So, the key liver disease that leads to increased ALP is cholestatic liver disorder, which involves blockage or obstruction of the bile ducts.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\"><strong>3. What If They\u2019re Elevated?<\/strong><\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">AST (SGOT) is standard in the 20-40 UI\/L range. ALT is also present. These are two liver enzymes that are specific to the liver. When many liver cells are damaged or necrotic, both enzymes are &#8220;released&#8221; and massively released into the blood. AST (SGOT) is usually found in many organs, such as the liver, heart, muscles, kidneys, and brain. It is released into the bloodstream when one of these organs is damaged. For example, its concentration will increase in the blood after a heart attack or muscle damage. Therefore, this enzyme is not specific for liver injury.<\/span><\/p>\n<ul style=\"text-align: justify;\">\n<li><span style=\"font-size: 16px; color: #000000;\">If only mild to moderate elevation of AST, ALT, and ALP, it usually signals liver inflammation. Imagine your liver saying, \u2018Hey, I\u2019m not feeling my best today.\u2019 If this inflammation persists, it can lead to scarring (fibrosis). We\u2019ve got stages 0 (no scarring) to 4 (cirrhosis). But here\u2019s the good news: Fibrosis can be reversible if you catch it early. Like hitting the rewind button!&#8221;<\/span><\/li>\n<\/ul>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\"><strong>Let\u2019s discuss the Common Causes of Elevated Liver Enzymes.<\/strong><\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">&#8220;Ah, the million-dollar question: \u2018Doc, I don\u2019t drink like a pirate\u2014why are my liver enzymes acting up?\u2019 Well, here are some usual suspects:<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\"><strong>1. Fatty liver disease is when too much fat is in your liver cells<\/strong>. Can a fatty<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">liver cause high ALP?<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">2. The most common presentation of NAFLD will be incidental findings of abnormal LFTs. Typical findings in NAFLD are raised ALT and AST, with a preserved ALT: AST ratio of 1.5, raised gamma-glutamyl transferase (GGT) and, occasionally, raised alkaline phosphatase (ALP).<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">3. <strong>Viral Hepatitis:<\/strong> Those sneaky viruses (Hepatitis A, B, C) love to party in your liver cells.<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">4. <strong>Medications<\/strong>: Some meds can be the liver\u2019s frenemies.<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">5. What are the ten worst medications for your liver? Prescription drugs: Statins, antibiotics like amoxicillin-clavulanate or erythromycin, arthritis drugs like methotrexate or azathioprine, antifungal<\/span><br \/>\n<span style=\"font-size: 16px; color: #000000;\">drugs, and niacin. Steroids. Allopurinol for gout. Antiviral drugs for HIV infection.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">What are dangerously high liver enzyme levels?<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">The specific assessment of liver enzyme index is as follows: A liver enzyme index of 40-80 warns of the risk of fatty liver, viral hepatitis, or alcoholichepatitis. A liver enzyme index of 80-150 warns of impaired liver function, which may cause complications such as cirrhosis, cirrhosis of the liver, and ascites. Diabetes raises your risk of nonalcoholic fatty liver disease, a condition in which excess fat builds up in your liver even if you drink little or no alcohol. This condition occurs in at least half of those with type 2 diabetes. However, it is not a given that if you have type 2 diabetes, you will automatically develop fatty liver disease. Since obesity, insulin resistance, and high levels of triglycerides in the blood increase the risk of fatty liver disease, treating these other conditions can prevent its development.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 16px; color: #000000;\">\u201cSo, my dear viewers, next time you see those liver enzyme numbers, don\u2019t panic. Remember, it\u2019s like your liver sending a postcard: \u2018Hey, I\u2019m working here!\u2019 And if you\u2019re curious about your numbers, chat with your friendly neighbourhood hepatologist. Until next time, stay curious, stay healthy,<\/span><\/p>\n<p>&nbsp;<\/p>\n<div style=\"text-align: center;\"><span style=\"font-size: 16px; color: #800000;\"><em><span style=\"text-decoration: underline;\"><a style=\"color: #800000;\" href=\"https:\/\/websitedesigns.com.au\/elankanew\/elanka-newsletter-sign-up\/\" target=\"_blank\" rel=\"noopener\"><strong>Click here to receive your free copy of the eLanka Newsletter twice a week delivered directly\u00a0to\u00a0your\u00a0inbox!<\/strong><\/a><\/span><\/em><\/span><\/div>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Decoding Liver Enzymes: What You Need to Know &#8211; By Dr Harold Gunatillake Web :\u00a0doctorharold.com Symptoms of liver disease may not be present until the later stages of severe disease, elevated liver enzyme tests are sometimes the first indication of potential liver damage. Hello viewers, today we will discuss liver enzymes and their significance. Liver [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":139138,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"aside","meta":{"footnotes":""},"categories":[20,1103],"tags":[872,29811,67049,67048],"class_list":{"0":"post-139137","1":"post","2":"type-post","3":"status-publish","4":"format-aside","5":"has-post-thumbnail","7":"category-articles","8":"category-dr-harold-gunatillake","9":"tag-dr-harold-gunatillake","10":"tag-liver","11":"tag-liver-enzymes","12":"tag-liver-helth","13":"post_format-post-format-aside"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.7.1 (Yoast SEO v25.9) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Decoding Liver Enzymes: What You Need to Know - By Dr Harold Gunatillake - eLanka<\/title>\n<meta name=\"description\" content=\"Decoding Liver Enzymes: What You Need to Know - By Dr Harold Gunatillake Symptoms of liver disease may not be present until the later stages\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Decoding Liver Enzymes: What You Need to Know - By Dr Harold Gunatillake\" \/>\n<meta property=\"og:description\" content=\"Decoding Liver Enzymes: What You Need to Know - By Dr Harold Gunatillake Symptoms of liver disease may not be present until the later stages\" \/>\n<meta property=\"og:url\" content=\"https:\/\/websitedesigns.com.au\/elankanew\/decoding-liver-enzymes-what-you-need-to-know-by-dr-harold-gunatillake\/\" \/>\n<meta property=\"og:site_name\" content=\"eLanka\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/eLanka.com.au\/\" \/>\n<meta property=\"article:published_time\" content=\"2024-07-25T10:56:17+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2024-07-25T10:58:35+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/websitedesigns.com.au\/elankanew\/wp-content\/uploads\/2024\/07\/Symptoms-of-liver-disease.png\" \/>\n\t<meta property=\"og:image:width\" content=\"600\" \/>\n\t<meta property=\"og:image:height\" content=\"400\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"eLanka admin\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"eLanka admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"6 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/websitedesigns.com.au\/elankanew\/decoding-liver-enzymes-what-you-need-to-know-by-dr-harold-gunatillake\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/websitedesigns.com.au\/elankanew\/decoding-liver-enzymes-what-you-need-to-know-by-dr-harold-gunatillake\/\"},\"author\":{\"name\":\"eLanka admin\",\"@id\":\"https:\/\/websitedesigns.com.au\/elankanew\/#\/schema\/person\/f6e635b74ab35ef88a68a9973cacc5bd\"},\"headline\":\"Decoding Liver Enzymes: What You Need to Know &#8211; 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