{"id":68141,"date":"2021-07-03T05:52:33","date_gmt":"2021-07-03T05:52:33","guid":{"rendered":"https:\/\/websitedesigns.com.au\/elankanew\/?p=68141"},"modified":"2023-06-28T17:09:02","modified_gmt":"2023-06-28T17:09:02","slug":"pfizer-and-astrazeneca-are-winners-of-vaccines-but-pfizer-vaccine-offers-longer-term-protection-by-dr-harold-gunatillake","status":"publish","type":"post","link":"https:\/\/websitedesigns.com.au\/elankanew\/pfizer-and-astrazeneca-are-winners-of-vaccines-but-pfizer-vaccine-offers-longer-term-protection-by-dr-harold-gunatillake\/","title":{"rendered":"Pfizer and AstraZeneca are winners of vaccines, But Pfizer vaccine offers longer-term protection-by Dr Harold Gunatillake"},"content":{"rendered":"<h1 style=\"text-align: center;\"><span style=\"font-size: 28px; color: #339966;\">Pfizer and AstraZeneca are winners of vaccines, But Pfizer vaccine offers longer-term protection-<span style=\"color: #0000ff;\">by Dr Harold Gunatillake<\/span><\/span><\/h1>\n<p><img loading=\"lazy\" loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-77916 aligncenter\" src=\"https:\/\/websitedesigns.com.au\/elankanew\/wp-content\/uploads\/2021\/11\/Harold-Gunethilake.jpg\" alt=\"Harold-Gunethilake\" width=\"160\" height=\"160\" \/><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 20px; color: #000000;\">Both prevent hospitalization of cases who contract the Delta variant, <\/span><span style=\"font-size: 20px; color: #000000;\">being vaccinated with either vaccine- prior.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Total number of COVID-19 cases passes 181 million and more than 3.9 <\/span><span style=\"font-size: 20px; color: #000000;\">million deaths.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Covid-19 has now been reported on every continent.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">COVID-19 is a respiratory disease caused by the SARS-CoV-2 virus.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Currently, there are 127 candidate vaccines.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Today, there are 37 candidate vaccines in stage 3 clinical trials.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">So far, 19 vaccines have been authorized across several countries.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Both Pfizer and AstraZeneca are winners when there are so many other candidate <\/span><span style=\"font-size: 20px; color: #000000;\">vaccines?<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">There is more evidence that Pfizer vaccine offers longer-term protection.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Currently, the thought in Australia is that people under the age of 60 should <\/span><span style=\"font-size: 20px; color: #000000;\">preferentially get Pfizer, In the UK people under the age of 40 are advised to get <\/span><span style=\"font-size: 20px; color: #000000;\">Pfizer.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Atagi comprises independent infectious diseases physicians, microbiologists, <\/span><span style=\"font-size: 20px; color: #000000;\">epidemiologists, public health nurses, GPs, and consumer representatives. Its advice <\/span><span style=\"font-size: 20px; color: #000000;\">states there is \u201ca higher risk and observed severity of thrombosis [clotting] and <\/span><span style=\"font-size: 20px; color: #000000;\">thrombocytopenia [low platelet count] syndrome related to the use of AstraZeneca<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Covid-19 vaccine observed in Australia in the 50\u201359-year-old age group than <\/span><span style=\"font-size: 20px; color: #000000;\">reported internationally and initially estimated in Australia\u201d.<\/span><\/p>\n<p style=\"text-align: justify;\"><strong><span style=\"font-size: 20px; color: #000000;\">Website: www.Doctorharold.com<\/span><\/strong><\/p>\n<p style=\"text-align: center;\"><iframe loading=\"lazy\" title=\"YouTube video player\" src=\"https:\/\/www.youtube.com\/embed\/ctWO5GzNBL4\" width=\"560\" height=\"315\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\"><\/iframe><br \/>\n<span style=\"font-size: 20px; color: #000000;\">A new study appearing in the journal Nature Trusted Source suggests <\/span><span style=\"font-size: 20px; color: #000000;\">that the Pfizer-BioNTech COVID-19 vaccine offers long-lasting <\/span><span style=\"font-size: 20px; color: #000000;\">protection.<\/span><\/p>\n<p style=\"text-align: justify;\"><!--more--><br \/>\n<span style=\"font-size: 20px; color: #000000;\">The study, led by Dr. Ali Ellebedy, an immunologist at Washington University, in St. <\/span><span style=\"font-size: 20px; color: #000000;\">Louis, MO, examined the body\u2019s immune response as it manifests in the so-called <\/span><span style=\"font-size: 20px; color: #000000;\">germinal centers. Germinal centers are B cell structures in the lymph nodes.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">The team found that the B cells persisted in the germinal centers in the lymph nodes <\/span><span style=\"font-size: 20px; color: #000000;\">for almost 4 months after vaccination. Usually, these decline after 4\u20136 weeks, an <\/span><span style=\"font-size: 20px; color: #000000;\">immunologist explained to The New York Times.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">B cells or the memory cells produced by the immune system in your body offers longlasting protection with Pfizer, compared to other vaccines. This is true, according to a <\/span><span style=\"font-size: 20px; color: #000000;\">new study appearing in Nature.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">The study examined the body\u2019s immune response at its root level the germinal <\/span><span style=\"font-size: 20px; color: #000000;\">centers- B cell structures in the lymph nodes.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">In the Accelerated article Review heading SARS-CoV2 mRNA vaccines induced <\/span><span style=\"font-size: 20px; color: #000000;\">persistent human germinal center responses was 95% effective in preventing <\/span><span style=\"font-size: 20px; color: #000000;\">coronavirus disease.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">The germinal center is a specialized microstructure in the lymphoid glands that <\/span><span style=\"font-size: 20px; color: #000000;\">forms in producing long-lived antibody secreting plasma cells and memory B cells, <\/span><span style=\"font-size: 20px; color: #000000;\">producing a potent immune response against foreign antigens, and in this present <\/span><span style=\"font-size: 20px; color: #000000;\">discussion is the severe acute respiratory syndrome-Coronavirus 2 i.e., SARS-CoV-2) <\/span><span style=\"font-size: 20px; color: #000000;\">messenger RNA (mRNA) based vaccine. <\/span><span style=\"font-size: 20px; color: #000000;\">Germinal centers develop in the B cell follicles of secondary lymphoid tissue during T <\/span><span style=\"font-size: 20px; color: #000000;\">cell-dependent antibody responses.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Emphasizing that the Germinal centers allow B cell formation, plasma cell formation, <\/span><span style=\"font-size: 20px; color: #000000;\">and immunoglobulins.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">It was revealed that the B cell persisted in the germinal centers for almost 4 months<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">after vaccination with Pfizer.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Germinal centers persist for about 3 weeks following immunization, but after this, <\/span><span style=\"font-size: 20px; color: #000000;\">memory B blasts continue to proliferate in follicles throughout the months of T celldependent antibody responses.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Does Pfizer vaccine protect against variants?<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Pfizer says COVID vaccine is highly effective against Delta variant.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">A study by researchers from the University of Texas together with Pfizer and <\/span><span style=\"font-size: 20px; color: #000000;\">BioNTech and published this month by Nature journal found that antibodies elicited <\/span><span style=\"font-size: 20px; color: #000000;\">by the vaccine were still able to neutralize all tested variants, including Delta, albeit <\/span><span style=\"font-size: 20px; color: #000000;\">at reduced strength.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">First identified in India, Delta is becoming the globally dominant variant of the <\/span><span style=\"font-size: 20px; color: #000000;\">coronavirus, according to the World Health Organization. <\/span><span style=\"font-size: 20px; color: #000000;\">&#8220;The data we have today, accumulating from research we are conducting at the lab<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">and including data from those places where the Indian variant, Delta, has replaced <\/span><span style=\"font-size: 20px; color: #000000;\">the British variant as the common variant, point to our vaccine being very effective, <\/span><span style=\"font-size: 20px; color: #000000;\">around 90%, in preventing the coronavirus disease, COVID-19,&#8221; Alon Rappaport,<\/span><span style=\"font-size: 20px; color: #000000;\">Pfizer&#8217;s medical director in Israel, told local broadcaster Army Radio.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">What about AstraZeneca vaccine?<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Delta variant of concern, first identified in India, is associated with a higher risk of <\/span><span style=\"font-size: 20px; color: #000000;\">hospitalization among the unvaccinated.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">A recent analysis from Public Health England (PHE) looks at how likely people who <\/span><span style=\"font-size: 20px; color: #000000;\">had an infection with the delta variant were to need treatment in the hospital.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">COVID-19 vaccines made by Pfizer (PFE.N) and AstraZeneca (AZN.L) offer high <\/span><span style=\"font-size: 20px; color: #000000;\">protection of more than 90% against hospitalization from the Delta coronavirus <\/span><span style=\"font-size: 20px; color: #000000;\">variant, a new analysis by Public Health England (PHE <\/span><span style=\"font-size: 20px; color: #000000;\">Pfizer\/BioNTech COVID-19 vaccine was 96% effective against hospitalization from <\/span><span style=\"font-size: 20px; color: #000000;\">the Delta variant after two doses, while Oxford\/AstraZeneca&#8217;s offered 92% protection <\/span><span style=\"font-size: 20px; color: #000000;\">against hospitalization by Delta.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">The report puts the protection from requiring hospital treatment for COVID-19 at <\/span><span style=\"font-size: 20px; color: #000000;\">71% after one dose and at 92% after two doses of the Oxford-AstraZeneca vaccine.<\/span><span style=\"font-size: 20px; color: #000000;\">The Pfizer vaccine was 94% effective at preventing hospitalization after the first dose <\/span><span style=\"font-size: 20px; color: #000000;\">and 96% after two doses.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Analysis reveals that although the Delta variant reduces the effectiveness of vaccine <\/span><span style=\"font-size: 20px; color: #000000;\">against symptomatic infection, two doses of either Pfizer or AstraZeneca vaccines <\/span><span style=\"font-size: 20px; color: #000000;\">still protect against severe infection.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Benefit of mixing different brands.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Oxford Vaccine Group\u2019s Com-Covid vaccine trial has examined the benefits of mixing <\/span><span style=\"font-size: 20px; color: #000000;\">different brands of COVID-19 vaccines between the first and the second dose. The <\/span><span style=\"font-size: 20px; color: #000000;\">results revealed that all combinations worked well, triggering an immune response.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Namely, the trial examined the efficacy of two doses of Pfizer-BioNTech, two doses of <\/span><span style=\"font-size: 20px; color: #000000;\">AstraZeneca, and one of them followed by the other in 850 people aged 50 years and <\/span><span style=\"font-size: 20px; color: #000000;\">older.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">The results revealed that all combinations worked well, triggering an immune<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">response.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Moderna vaccine<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">In a new study, not yet peer-reviewed, scientists from Moderna found that antibodies <\/span><span style=\"font-size: 20px; color: #000000;\">from vaccinated clinical trial volunteers could effectively neutralize a model virus <\/span><span style=\"font-size: 20px; color: #000000;\">that carries the SARS-CoV-2 spike protein with the delta variant mutations.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">The team investigated how well serum from eight trial volunteers could neutralize <\/span><span style=\"font-size: 20px; color: #000000;\">the model virus, or pseudo virus. They made a number of these pseudo viruses to <\/span><span style=\"font-size: 20px; color: #000000;\">represent the delta variant and other variants of concern, including the alpha variant, <\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">first identified in the United Kingdom, and the beta variant, first identified in South <\/span><span style=\"font-size: 20px; color: #000000;\">Africa.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">FDA will add warning to Moderna, Pfizer vaccine fact sheets about \u2018extremely rare <\/span><span style=\"font-size: 20px; color: #000000;\">side effect.\u2019<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">The Food and Drug Administration (FDA) plans to add a warning to Pfizer\u2019s and <\/span><span style=\"font-size: 20px; color: #000000;\">Moderna\u2019s COVID-19 vaccine fact sheets about the rare risk of developing heart <\/span><span style=\"font-size: 20px; color: #000000;\">inflammation after receiving the injection.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">The news comes after a Centers for Disease Control and Prevention (CDC) safety <\/span><span style=\"font-size: 20px; color: #000000;\">panel has reviewed the evidence and concluded there is a \u201clikely association\u201d<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">between cases of myocarditis and pericarditis and receiving the Moderna and Pfizer <\/span><span style=\"font-size: 20px; color: #000000;\">shots in people aged 30 years and younger.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Hope this video talk was useful,<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">You can always contact me online for any advice on health issue.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">I am committed and dedicated to render that service to our community worldwide.<\/span><br \/>\n<span style=\"font-size: 20px; color: #000000;\">Thank you, Stay safe and goodbye for now.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 20px;\"><em>Disclaimer:<\/em><\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 20px;\"><em>The information contained in this article is for general information purposes only, and whilst the author will endeavour to keep the information up to date and correct, eLanka makes no representations or warranties of any kind, express or implied, about the completeness, accuracy, reliability, suitability or availability with respect to the eLanka website or the information, products, services, or related graphics contained in this article for any purpose. 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COVID-19 [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":116942,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"aside","meta":{"footnotes":""},"categories":[20,1103],"tags":[13619,647],"class_list":{"0":"post-68141","1":"post","2":"type-post","3":"status-publish","4":"format-aside","5":"has-post-thumbnail","7":"category-articles","8":"category-dr-harold-gunatillake","9":"tag-covid-19","10":"tag-harold-gunatillake","11":"post_format-post-format-aside"},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.7.1 (Yoast SEO v25.9) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pfizer and AstraZeneca are winners of vaccines, But Pfizer vaccine offers longer-term protection-by Dr Harold Gunatillake<\/title>\n<meta name=\"description\" content=\"Both prevent hospitalization of cases who contract the Delta variant, being vaccinated with either vaccine- prior.Total number of COVID-19\" \/>\n<meta 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